CBD Oil Side Effects - What You Need to Know

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As research progresses there seems to be many health benefits of CBD. A simple search online for nearly any health problem you’re up against will show someone who found their solution with… CBD oil.

The health benefits of CBD cannot be denied, although there could be a risk of side effects. Compared to typical pain relievers, CBD oil side effects of could be deemed ‘mild’ and pale in comparison to the addictive qualities of prescription/over the counter (OTC) drugs. Make no mistake, believing there is no chance of adverse reaction is not wise. This article will discuss the side effects of CBD oil as well as show how CBD works in the body and eliminate some misconceptions about CBD.

CBD Oil Common Questions & Misconceptions

Are all CBD oils the same?

No, absolutely not. Many ingredients can go in to CBD products making each one unique, even when it comes to different batches from the same company. Some of the most common differences are:

  • Organic - are all ingredients organic?
  • Isolate, broad spectrum, or full spectrum - it makes a difference!
  • CBD oil from hemp (<0.3% THC) versus CBD oil from Marijuana
  • Pure CBD oil and CBD oil with additives like terpenes
  • Quantity of CBD - tinctures can vary from 25mg per 30ml to more than 5000mg!

CBD oil can get you high…

Incorrect. Every legal CBD oil available is required by law (the 2018 Farm Bill) to contain less than 0.3% THC - that is three tenths of one percent, not 3%. Each state has the right to determine legality for themselves, and ever state in the U.S. has their own statutes on CBD.

Is CBD oil addictive?

No. Not only is it not addictive, the human body has an endocannibinoid system (ECS) that requires the essential oils, many of which are derived from the hemp plant and contained in CBD along with over 200 other cannabinoids.

How does CBD affect the body?

Naturally, your body, CBD, and endocannabinoid system (ECS) all work in unison to achieve an optimal state of health. When a nutritional deficiency occurs, the human body will adapt and typically yell for help in the form of pain. This is where CBD oils could be a tremendous help but the science has yet to be proven.

Plant derived oils known as phytochemicals (in CBD - phytocannabinoids) are very similar to the compounds created and required by our own bodies. Your ECS controls a large portion of functionality both in the brain and body including cognitive function, memory, mood, immune response, pain perception, temperature regulation, and more. Maintaining balance is the overall goal of the endocannabinoid system, homeostasis in scientific terms. Cannabiniod binds with receptors in the ECS to help regulate after consumption without any psyhcoactive effects as no THC exists in CBD isolate1.

Neurodegenerative conditions are one of many possible conditions CBD can affect. Molecular pathways are the ‘superhighways’ of the brain and facilitate the absorption of CBD in the brain, the same pathways affecting MS, certain types of cancers, and even anxiety2. Specifically, the CB1 and CB2 receptors are responsible for CBD absorption. When no THC is present, these receptors are available to attract cannabidiol.

CBD and Addiction

According to the World Health Organization’s Expert Committee on Drug Dependence in their Cannabidiol (CBD) Critical Review Report3:

"The range of conditions for which CBD has been assessed is diverse, consistent with its neuroprotective, antiepileptic, hypoxia-ischemia, anxiolytic, antipsychotic, analgesic, anti-inflammatory, anti-asthmatic, and antitumor properties."

In addition, potential benefits listed in a 2015 research paper on the use of CBD as an intervention for addictive behaviors include4:

“A limited number of preclinical studies suggest that CBD may have therapeutic properties on opioid, cocaine, and psychostimulant addiction, and some preliminary data suggest that it may be beneficial in cannabis and tobacco addiction in humans.”

CBD Side Effects

Decades of research has shown prescription and over the counter medications to be much more dangerous than CBD, the side effects of which are mild in comparison5. Special attention is to be paid when CBD is used with other medications, and as always, it is highly suggested you refer to your healthcare professional when considering beginning any CBD dosage.

No matter what the uses are for CBD oil for addiction, there are potential side effects. One hundred thirty two studies were reviewed and found safety parameters were not altered including5:

  • Dry Mouth; common when using CBD as the terpene Delta 3 Carene dries out the body
  • Lower Blood Pressure; while many consider lower blood pressure to be a benefit, for those with health conditions or using blood thinners, this could pose a concern
  • Dizziness; with higher doses especially, dizziness could occur, often described as having a feeling of ‘light-headedness’ prior
  • Diarrhea; CBD is one phytochemical that has high gatroprotective qualities, and as a result it is normally not CBD but other ingredients that cause discomfort and diarrhea but the carrier or other ingredients such as terpenes and other phytochemicals.
  • Additional Medications; the liver is responsible for the metabolization of drugs and CBD could interact with the ability to process certain drugs by impeding their absorption. As a result, it is always recommended that anyone beginning a CBD regimen discuss their personal situation with their healthcare professional prior to use.

If you are investigating CBD and are considering its use, visit our products page for our Original, Focus, or Tranquil CBD - all natural, 100% U.S. sourced ingredients.


1. Zou, Shenglong, and Ujendra Kumar. “Cannabinoid Receptors and the Endocannabinoid System: Signaling and Function in the Central Nervous System.” International journal of molecular sciences vol. 19,3 833. 13 Mar. 2018, doi:10.3390/ijms19030833
2. Maroon, Joseph, and Jeff Bost. “Review of the neurological benefits of phytocannabinoids.” Surgical neurology international vol. 9 91. 26 Apr. 2018, doi:10.4103/sni.sni_45_18
3. World Health Organization, Expert Committee on Drug Dependence. “CANNABIDIOL (CBD) Critical Review Report.” 2018. PDF file. https://www.who.int/medicines/access/controlled-substances/CannabidiolCriticalReview.pdf
4. Prud’homme, M., R. Cata, and D. Jutras-Aswad, “Cannabidiol as an intervention for addictive behaviors: a systematic review of the evidence.” Substance abuse: research and treatment, 2015.
5. Iffland, Kerstin, and Franjo Grotenhermen. “An Update on Safety and Side Effects of Cannabidiol: A Review of Clinical Data and Relevant Animal Studies.” Cannabis and cannabinoid research vol. 2,1 139-154. 1 Jun. 2017, doi:10.1089/can.2016.0034